VINPOCETINE“Vinpocetine is one of the few substances studied which can offer multiple cognitive benefits as well as a remarkable number of benefits for the body. It turns up our mind and keeps our lights bright at the same time in that it helps our cardiovascular and GI systems, along with muscles, joints, and sensory organs to function better.” Jha, M., Rahman, M., & Sheikh, H. (2011). Vinpocetine: A Smart Drug and a Smart Nutrient. The International Journal of Pharmaceutical Sciences and Research, 3(2), 346-352.
A Vinpocetine supplement boosted verbal recall by 12% and sped up executive function by 21% in a double-blind, placebo-controlled study. Solomon et al. The Journal of Human Psychopharmacology: Clinical and Experimental. (2015).
Improves memory, enhances alertness, and delays age-related cognitive decline. Jha, M., Rahman, M., & Sheikh, H. (2011). Vinpocetine: A Smart Drug and a Smart Nutrient. The International Journal of Pharmaceutical Sciences and Research, 3(2), 346-352.
Enhances oxygen and nutrient delivery to brain cells while fighting oxidative stress. Jha, M., Rahman, M., & Sheikh, H. (2011). Vinpocetine: A Smart Drug and a Smart Nutrient. The International Journal of Pharmaceutical Sciences and Research, 3(2), 346-352.
Increases blood flow and metabolism within the brain. Szapáry, L., Fehér, G., & Bagoly, E. (2007). The Role of Vinpocetine in the Treatment of Cerebrovascular Diseases Based in Human Studies. Hungarian Medical Journal, 148(29), 1353-8.
PHOSPHATIDYLSERINEPromotes memory formation and improves recall. Einstein, G., Maier, S., & McDaniel, M. (2003). “Brain-Specific” Nutrients: a Memory Cure? Nutrition, 19, 957-75; Massari, D., Nunzi, M., Petrie, W., Yesavage, J., Tinklenberg, J., & Crook, T. (1991). Effects of Phosphatidylserine in Age-Associated Memory Impairment. Neurology, 41, 644-9.
Boosts the brain’s processing speed and reduces reaction time.
Leech et al. Alzheimer’s Association International Conference. (June 2015)
Alleviates stress and anxiety. Baumeister, J., Barthel, T., Geiss, K., & Weiss, M. (2008). Influence of Phosphatidylserine On Cognitive Performance And Cortical Activity After Induced Stress. Nutritional Neuroscience,11(3), 103-110; Hellhammer, J., Fries, E., Buss, C., Engert, V., Tuch, A., Rutenberg, D., et al. (2004). Effects of Soy Lecithin Phosphatidic Acid And Phosphatidylserine Complex (PAS) On The Endocrine And Psychological Responses To Mental Stress. Stress: The International Journal on the Biology of Stress, 7(2), 119-126.
Increases the supply of acetylcholine in the brain, which–in addition to enhancing focus, memory and neuromuscular control–combats age-related cognitive decline.
Lerer, B., Oppenheim, Y., Kelly, D., Gorfine, M., Kampf-Sherf, O., & Schreiber, S. (2000). An Open Trial of Plant Source Derived Phoshpatidylserine for Treatment of Age-Related Cognitive Decline. The Israel Journal of Psychiatry and Related Sciences, 37(4), 302-7; Kidd, P. (2005). Neurodegeneration from Mitochondrial Insufficiency: Nutrients, Stem Cells, Growth Factors and Prospects for Brain Rebuilding Using Integrative Management. Alternative Medicine Review: A Journal Of Clinical Therapeutic Disciplines, 10(4), 268-93.
L-TYROSINEImproves mental endurance and minimizes reaction time. Jäger, R., Purpura, M., Olson, M., Hoffman, M., Beller, N., Gonzalez, A., et al. (2010). The Effects of Acute and Prolonged CRAM Supplementation on Reaction Time and Subjective Measures of Focus and Alertness in Healthy College Students. Journal of International Society of Sports Nutrition, 7, 39.
Increases motivation and happiness by catalyzing dopamine turnover. Growdon, J. H., Melamed, E., Logue, M., Hefti, F., & Wurtman, R. J. (1982). Effects of Oral L-Tyrosine Administration Of CSF Tyrosine And Homovanillic Acid Levels In Patients. Life Sciences, 30(10), 827-832.
Supports fat loss. Meijssen, S., Erkelens, D., Bilecen, S., Derksen, R., Ballieux, C., & Cabezas, M. (2001). Insulin Mediated Inhibition of Hormone Sensitive Lipase Activity In Vivo In Relation To Endogenous Catecholamines In Healthy Subjects. Journal of Clinical Endocrinology & metabolism, 86(9), 4193-4197.
Elevates mood while supporting memory and learning.
Deijen, J., & Orlebeke, J. (1994). Effect of Tyrosine on Cognitive Function And Blood Pressure Under Stress. Brain Research Bulletin, 33(3), 319-323; Grevet, E. H., Tietzmann, M. R., Shansis, F. M., Hastenpflug, C., Santana, L. C., Forster, L., et al. (2002). Behavioral Effects Of Acute Phenylalanine And Tyrosine Depletion In Healthy Male Volunteers. Journal of Psychopharmacology, 16(1), 51-55.
ALPHA GPCCatalyzes the production of acetylcholine, a neurotransmitter that supports memory, cognition and neuromuscular control. Blusztajn, J. (1998). Choline, a Vital Amine. Developmental Neuroscience,281(5378), 794-795.
Zeisel, S. (2000). Choline: an Essential Nutrient for Humans. Nutrition, 16, 669-71.
Improves cognitive function while reducing oxidative stress on the brain. Shea, T., Suchy, J., & Chan, A. (2009). Dietary Supplementation with a Combination of α-lipoic Acid, Acetyl-l-carnitine, Glycerophosphocoline, Docosahexaenoic Acid, and Phosphatidylserine Reduces Oxidative Damage to Murine Brain and Improves Cognitive Performance. Nutrition Research, 29(1), 70 – 74.
Delays age-related cognitive and memory decline.
Blusztajn, J. (1998). Choline, a Vital Amine. Developmental Neuroscience,281(5378), 794-795; Zeisel, S. (2000), Choline: an essential nutrient for humans. Nutrition, 16, 669-71.
HUPERZINE ADouble-blind, clinical research continues to suggest that Huperzine A safely enhances memory and learning in human participants. McDougall, G. J., Austin-Wells, V., & Zimmerman, T. (2005). Utility of Nutraceutical Products Marketed For Cognitive And Memory Enhancement. Journal of Holistic Nursing, 23(4), 415-433.
Huperzine A enhances focus, retention and muscular control by increasing the supply of acetylcholine in the brain. Raves, M., Harel, M., Pang, Y., Silman, I., Kozikowski, A., & Sussman, J. (1997). Structure of Acetylcholinesterase Complexed with the Nootropic Alkaloid Huperzine A. Nature Structural Biology,4, 57 – 63.
Huperzine A is also a safe and effective remedy for Alzheimer’s disease. Mazurek, A. (1999). An Open Label Trial of Huperzine A in the Treatment of Alzheimer’s Disease. Alternative Therapies, 5(2:97), 97-98.
Huperzine supplementation has been shown to increase peak Alpha frequency, a manifestation of flow, i.e. sustained focus.
Leech et al. Alzheimer’s Association International Conference. (June 2015)
ACETYL-L-CARNITINEFights age-related decline in mental function. Ramacci, M., Cairns, M., Wilton-Cox, H., & Dowson, J. (1992). The Morphology of Lipopigment in Rat Purkinje Neurons After Chronic Acetyl-L-Carnitine Administration. Biological Psychiatry, 32(2), 179-87.
Ancona, L., Calvani, M., Janiri, L., Pirrongelli, C., Casella, L., & Tempesta, E. (1987). Acetyl-L-Carnitine in Depressed Subjects. Drugs Under Experimental and Clinical Research, 13(7), 417-23. Zotti, C., Petrelli, G., Lecciso, G., Fiore, A., Corallo, D., & Garzya, G. (1990). Evaluation of the Effects of Acetyl-L-Carnitine on Senile Patients Suffering from Depression. Drugs Under Experimental and Clinical Research,16(2), 101-6.
Boosts mental energy and focus.
Pistarini, C., Fugazza, G., & Guarnaschelli, C. (1988). Pathological Brain Aging: Evaluation of the Efficacy of a Pharmacological Aid. Drugs Under Experimental and Clinical Research, 14(11), 715-8.